Monday, 19 January 2015

Frequently Asked Questions about Immunotherapy Treatments for Urinary Bladder Cancer .

If you’re trying to find out what are Immunotherapy treatments for Urinary bladder cancer are, and want to save yourself a lot of time and effort compiling which is effective and approved versus which is not and won’t be as effective, then this blog-post will serve to be your guide as we answer all the common questions about these different therapies.

What is Immunotherapy?
It’s the use of different treatment to suppress, induce or enhance an immune response, in this case to treat urinary bladder cancer.
www.gapsos.com
www.gapsos.com

What are the types of treatments for Urinary Bladder cancer?
There are actually 4 types of treatments, some of which are FDA-approved, others undergoing clinical trials, here they are:
a.       Monoclonal Antibodies (MABs).
B.       Vaccine Based immunotherapy.
c.       Non-FDA approved drugs.
d.       Intravesical immunotherapy:

Which main treatment out of all of them is fully approved by the FDA?
The Intravesica ltreatment has been approved by FDA for the treatment of urinary bladder cancer, specifically Bacillus Calmette-Guerin (BCG) which is the most efficient intravesicaltreatment which is used for the treatment of early stage bladder cancer.

What exactly is BCG?
 BCG is a bacterium which is associated to the germ and it causes tuberculosis, but it does not generally cause serious types of diseases.

What exactly is BCG used for?
BCG is indicated for the prophylaxis and treatment of carcinoma in situ of urinary bladder cancer, and used for the prophylaxis of primary stage Ta or T1 papillary tumors following transurethral resection (TUR). BCG is not suggested for the stage TaG1 papillary tumors, if they are concluded to be at high risk of tumor repetition.
Although it’s advised not to be used in immunosuppressed patients or patients with acquired or congenital immune deficiencies, whether due to immunosuppressive therapy, cancer therapy or concurrent disease such as AIDS.

Is there are any noted side-effects?
Yes, the most common side effects include: Hematuria, flu-like syndrome, urinary frequency, dysuria, malaise/fatigue, fever, nausea/vomiting, rigors, cramps/pain, nocturia, urgency, and cystitis.

Is there are any other prominent drugs from the mentioned types that could be used in Urinary Bladder Cancer treatment?
Everolimus, Sorfenib, and Suitinib may have a high potential for the treatment of urinary bladder cancer because these are currently under ongoing clinical tests and also many tests have shown that they possess a significant anti-cancer effect depending on different phases of cancer.

Global Allied Pharmaceuticals (GAP) is one of the emerging organizations in pharma industry. We provide immunotherapy services worldwide. Contact us on www.gapsos.com, to know more about us.

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