If you’re looking for an introduction to
immunotherapy and its different applications, this blog-post will save you a
lot of headache and will show the different applications of this type of
treatment in layman language.
We’ll be introduced as to what is
Immunotherapy, its different types and uses, and we’ll go through with only two
types as a start.
First of all what is immunotherapy?
It is the treatment of any type of disease,
through the enhancement,suppression, or induction of a response from the immune
system.
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And to simplify it even further, it’s used to
either amplify or suppress an immunityeffect.
Now that we know what it’s about, let’s get to
understand its different types as follows:
There are two main types: Activation &
Suppression Immunotherapies, and other approaches which will introduce in other
posts.
We’ll get to exploring them more in detail in
other articlesbut before we’re capable of understanding them we have to
understand what are immune modulators.
Immuno-modulators are mainly the active
agents of this type of treatment, and they’re made of various preparations,
that could be natural, synthetic or even recombinant, Cytokines are often the
case, but let’s take a look at several examples of them:
1-Cytokines:Interferons, G-CSF
2-ChemoKines:CCL3, CCL26
3-Interleukins: IL2 – IL-12
4-others: cytosine phosphate guano
sine,glucans.
What makes these type of active agents
attractive for usage as a regimen is that they often have side effects that are
not as strong or unfavorable as drugs and also create less resistance when it
comes to microbial diseases.
The main type of treatment these
immunomodulators are used for is called cell based immunotherapies , which has
proven to be effective for some kind of cancer , Immune effector cells are like
natural killer cells , dendritic cells ,
macrophages , cytotoxic t lymphocytes …etc. .
Mainly the way to work to protect the body is
by targeting abnormal antigen on the surface of the cancerous cells that have
mutated.
And thus in this blogpost you were introduced
to what is Immunotherapy and its different types and how they actually battle
different types of diseases by modification of the immune response and you
understood the 2 main types briefly whether it’s activation or suppression and
what exactly are immunomodulators , now you have a basic grasp of it .
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