Frequently Asked Questions about the Main Functions of Antibodies & How the Work in the Prenatal Stages in the Science of Immunotherapy.

If you want to understand the basic functions of antibodies and how they work and thus used a lot in the field of antibody immunotherapy, then you’ll want to read this Q&A blogpost about its functions and how it works in the prenatal and neonatal stages of human life.

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So what is antibody immune-oncology again?

If you can’t find a way to differentiate the host’s cells from the pathogen or foreign body, then you won’t be able to eradicate it, that’s the way the antibodies work, they detect antigen proteins that aren’t natural within the body and either bind to it and attack these cells or inform the immunity to act on its part.

And how do these antibodies function precisely?

Mainly antibodies can be useful in either secreted soluble form where it’s active in finding antigens or in the form of membranes where it transforms to memory cells that can help the immune system in finding a pathogen antigen that it has detected before, more like the different between new detectives and experienced detectives.

And from where are these antibodies produced?

When the B cells are activated they differentiate into plasma cells, then these plasma cells secrete these antibodies or they differentiate into memory cells that we’ve mentioned, that make the immune response to pathogens fast.

Could you tell you more about how a baby is protected from pathogens when he’s still inside his mother and the antibodies role in that?

Mainly this happens through a phenomenon that is called passive immunization that is provided from the mother and is transferred to the fetus in the form of antibodies in its bloodstream and thus based on that they’re considered a part of the humoral immune system.

While when it comes to the endogenous production of antibodies within the fetus, it varies depending on the different types of antibodies.

And what produces these circulating antibodies?

The production of these antibodies is resulted from clonal B cells that specifically respond to a single type of antigen for example a virus capsid protein fragment.

And can you state how these antibodies contribute to the immunity of the host?

Sure it can contribute in three ways: preventing the entrance of pathogens and their damaging effects, stimulation of immune cells that remove or eat the pathogens and lead to the triggering of pathogenic cells destruction through the immunity.

And thus this wraps up our quick Q&A session on antibody functions and its connection to immunotherapy.

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