Monday 2 February 2015

Uterine cancer patients can be treated with advanced treatment such as immunotherapy.

Uterine cancer is one the leading causes of death related to cancer like disease across the world. The majority of uterine cancer is adenocarcinomas which include serous, mucinous, clear cell, and mixed cell. The epithelial non adenocarcinomas include squamous cell carcinoma, small cell carcinoma, transitional cell carcinoma, and undifferentiated carcinoma. Immunotherapy treatments have various immunotherapeutic cancer agents which are used in all types of this cancer.


www.gapsos.com
www.gapsos.com


Several risk factors are observed that involve age (postmenopausal after the age of 55 years, incidence rate is higher than 95 per 100,000 people in the age of 65 Years), endogenous estrogen exposure ( it causes early menarche, nulliparity, infertility, late menopause, and estrogen producing tumor), exogenous estrogen (Hormonal ReplacementTherapy and drugs such as  Tamoxifen), past medical history (diabetes mellitus, and hypertension), history of endometrial atypical hyperplasia, family history (less than 1% of uterine cancer is due to familial factors), history of breast cancer, and genetic factors (mutations in the MLH1 or MSH2 Gene cause of defect in hereditary nonpolyposis colorectal cancer  have 20% risk to developing endometrial cancer before the age of 50 years, and 60% risk after the age of 60 years)
Various symptoms were observed in the advanced stage of this cancer that involves vaginal bleeding in unexpected postmenopausal women (menorrhagia or metrorrhagia ).Profuse watery discharge is another symptoms.Attention should be paid to the duration and severity of the symptoms.

The significant role play by immunotherapeutic cancer agent in Immunotherapy for  the treatment of uterine cancer that involve monoclonal antibody drug, vaccine based immunotherapy, adoptive T cell therapy. Kinase inhibitors, cytokines, and checkpoint inhibitors. These immunotherapeutic cancer agents have common actions that are increasing the potential of patient’s immune system to fight with specific cancer’s cell. In the present time, no single immunotherapy based drug has received approval by the Food and Drug Administration (FDA) for the treatment of this cancer, but much more are under evaluation via passes through several pre clinical and clinical phases (phase 1, phase 2, and phase 3) for FDA approval.

Bevacizumab is a monoclonal antibody drug  is running in clinical trials (phase 2) under evaluation of safety and efficacy, and for FDA approval. This drug inhibits the growth of specific cancer’s cell via blocking the way of blood flow to the site of cancer. 

Global Allied pharmaceuticals (GAP) have number of immunotherapeutic cancer agents for the treatment of cancer like disease such as uterine. GAP has a responsible team of expert for immunotherapy and antibody drug conjugates.
For more information kindly visit us at www.gapsos.com

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