Thursday 1 January 2015

Immunotherapy is a very viable treatment option for women patients suffering from cervical cancer.

Cervical cancer arise in the cells of the cervix (cervix is the lower part of the uterus in the human female reproductive system). This cancer is one of the leading causes of death across the world. With the availability of newer tools and technologies, it is easy to detect it in starting phase.
Cervical cancer is the seventh most common cancer across the world and it represents 85% of all cancers. About 12,360 new cases and 4,020cases of death due to cervical cancer are estimated in 2014. Etiologic factors of this cancer are human papillomavirus (HPV) infected, cigarette smoking, weakened immune system, having a multiple pregnancy, sexual activity and oral contraceptives.
www.gapsos.com
www.gapsos.com

Cervical cancer is classified into four types, which involve Squamous cell carcinoma (90 %), Adenocarcinoma (10%), while small cell and neuroendocrine carcinoma, and Adenosqaumous carcinomas both are rarely observed.  Squamous cell carcinoma is originated from metaplastic squamous epithelium located between the original and new squamocolumnar junctions, the transformation zone. Adenocarcinoma originates from glandular cells. Adenosqaumous carcinomas are originated from the cell lining of the cervix and gland cells. Small cell and neuroendocrine carcinoma originates from neuroectodermal cells like argyrophilic, neuroendocrine, and melanocytic cells. HPV infection is the most common cause of squamous cell cancer and adenocarcinoma.

There are some immunotherapy agents are approved by the Food and Drug Administration (FDA) that involves Cervarix and Gardasil for the treatment of cervical cancer.

Cervarix is a vaccine which is indicated for prevention of cervical cancer caused by oncogenic HPV 16 and 18, but it does not provide protection against disease due to all HPV types. Some adverse effects are observed, which includes headache, gastrointestinal symptoms and myalgia. Gardasil is also a vaccine to protect against cervical cancers, which is caused by HPV types 16 and 18. Some contraindications are observed like severe allergic reactions to yeast and hypersensitivity. Some adverse effects are also being noted that involves headache, fever, swelling at the injection site and many more. 

Global Allied Pharmaceuticals (GAP) has progressive approaches for treatment of cervical cancer. GAP has a team of experts in immunotherapy and immune-oncology. Our experts gather all the information related to the patients suffering from this cancer and then they provide their analysis.

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